Amlodipine, sold under the brand name Norvasc among others, is a medication used to treat high blood pressure and coronary artery disease.
The reference site for Amlodipine
WHAT IS AMLODIPINE?
Amlodipine is a long-acting calcium channel blocker used as an anti-hypertensive, and in the treatment of angina.
As with other calcium channel blockers, amlodipine acts by relaxing the smooth muscles in the arterial wall, decreasing peripheral resistance and hence improving blood pressure. In angina it improves blood flow to the myocardium. It was developed under the direction of Dr. Simon Campbell.
Amlodipine is marketed as Norvasc®, as well as under various other names.
Brand Name(s): Norvasc
CAS nº: 88150-42-9
The sections below will provide you with more specific information and guidelines related to amlodipine and its correct use. Please read them carefully.
Amlodipine was approved by the Food and Drug Administration (FDA) in 1995.
Please visit the official site of the FDA for further information.
Why is this medication prescribed?
Amlodipine is a calcium channel blocker used to treat angina (chest pain) and high blood pressure. Amlodipine affects the movement of calcium into the cells of the heart and blood vessels. As a result, amlodipine relaxes blood vessels and increases the supply of blood and oxygen to the heart while reducing its workload.
High blood pressure adds to the workload of the heart and arteries. If it continues for a long time, the heart and arteries may not function properly. This can damage the blood vessels of the brain, heart, and kidneys, resulting in a stroke, heart failure, or kidney failure. High blood pressure may also increase the risk of heart attacks. These problems may be less likely to occur if blood pressure is controlled.
This medication can sometimes be prescribed for other uses, but it is strongly recommended that you ask your doctor or pharmacist for more information.
Other uses for this medicine
This medication may be prescribed for other uses. However, before using this medication, it is strongly advised that you consult your doctor or pharmacist for further information.
Dosage and using this medicine
Amlodipine comes as an orally-administered tablet, and is usually taken once a day. To help you remember to take amlodipine, take it around the same time every day.
Adults: The usual initial antihypertensive oral dose of amlodipine is 5 mg once daily with a maximum dose of 10 mg once daily. Small, fragile, or elderly individuals, or patients with hepatic insufficiency may be started on 2.5 mg once daily and this dose may be used when adding amlodipine to other antihypertensive therapy.
Dosage should be adjusted according to each patient’s need. In general, titration should proceed over 7 to 14 days so that the physician can fully assess the patient’s response to each dose level. Titration may proceed more rapidly, however, if clinically warranted, provided the patient is assessed frequently.
The recommended dose for chronic stable or vasospastic angina is 5-10 mg, with the lower dose suggested in the elderly and in patients with hepatic insufficiency. Most patients will require 10 mg for adequate effect.
The recommended dose range for patients with coronary artery disease is 5-10 mg once daily. In clinical studies the majority of patients required 10 mg.
Children: The effective antihypertensive oral dose in pediatric patients ages 6-17 years is 2.5 mg to 5 mg once daily.
What special precautions should I follow?
Before taking amlodipine:
Tell your doctor and pharmacist if you are allergic to amlodipine or any other medications.
Inform your doctor and pharmacist what prescription and non-prescription medications, vitamins, nutritional supplements, and herbal products you are taking.
Moreover, please tell your doctor if you have or have ever had heart failure or liver disease.
Additionally, let your doctor know if you are pregnant, plan to become pregnant, or are breast-feeding.
What should I do if I forget a dose?
Take the missed dose as soon as you remember it. However, if it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule.
Never take a double dose to make up for a missed one.
What side effects can this medication cause?
Possible side effects from amlodipine may include:
• feet or ankle swelling
Tell your doctor if any of these symptoms are severe or do not go away:
• swelling of the hands, feet, ankles, or lower legs
• upset stomach
• stomach pain
• dizziness or lightheadedness
• excessive tiredness
• flushing (feeling of warmth)
Additionally, if you experience any of the following symptoms, call your doctor immediately:
• more frequent or more severe chest pain
• rapid pounding
• irregular heartbeat
What storage conditions are needed for this medicine?
Always keep this medication in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from excess heat and moisture (not in the bathroom).
Also, please remember to throw away any medication that is outdated or no longer needed. If you have any questions, talk to your pharmacist about the proper disposal of your medication.
In case of an emergency/overdose
In the case of a suspected overdose, call your local poison control center on 1-800-222-1222. However, if the victim has collapsed or is not breathing, call the local emergency services on 911.
Symptoms of an amlodipine overdose may include:
• rapid heartbeat
PICTURES OF AMLODIPINE PILLS
Below you will find images and specific information on the principal types of amlodipine that exist, including their respective brand name(s), strength, inscription codes and manufacturers.
The information below includes general information and guidelines for patients taking this medication and should never be used to substitute professional medical advice that can be provided by a qualified physician or family doctor.
Strength(s): 5 MG
Imprint: Norvasc 5
Manufacturer: PFIZER US PHARM.
Strength(s): 10 MG
Imprint: Norvasc 10
Manufacturer: PFIZER US PHARM.